Babesiosis mu agalu: zizindikiro

 M'zaka zaposachedwa, pakhala pali milandu pamene babesiosis agalu amapezeka popanda zizindikiro zachipatala komanso popanda zotsatira zakupha. Komabe, pofufuza zopaka magazi zodetsedwa malinga ndi Romanovsky-Giemsa, babesia amapezeka. Izi zikuwonetsa kunyamula kwa tizilombo toyambitsa matenda. Matendawa, monga lamulo, amapangidwa mosiyana kwambiri: kuchokera ku poizoni kupita ku chiwindi cha chiwindi. Chochititsa chidwi kwambiri ndi Babesia pakati pa agalu osokera a mumzinda. Kukhalapo kwa tizilombo toyambitsa matenda timene timatulutsa Babesia canis pagulu la agalu osochera ndi njira yolumikizirana ndi epizootic ya matendawa. Titha kuganiza kuti nyamazi ndi nkhokwe ya tizilombo toyambitsa matenda, zomwe zimathandiza kuti zisungidwe. Chifukwa chake, titha kunena kuti dongosolo lokhazikika la parasite-host lapanga anthu osokera agalu. Komabe, pakadali pano ndizosatheka kudziwa ngati izi zidachitika chifukwa cha kufooka kwamphamvu komanso zowopsa za Babesia canis kapena chifukwa chakuchulukira kwa thupi la galu ku tizilombo toyambitsa matenda. Nthawi yoyamwitsa ya matenda amtundu wachilengedwe imatha masiku 13-21, pakuyesa matenda - kuyambira masiku 2 mpaka 7. Mu hyperacute njira ya matenda, agalu kufa popanda kusonyeza matenda zizindikiro. Kugonjetsedwa kwa thupi la galu Babesia canis pachimake cha matendawa kumayambitsa malungo, kuwonjezeka kwakukulu kwa kutentha kwa thupi mpaka 41-42 ° C, komwe kumasungidwa kwa masiku 2-3, ndikutsatiridwa ndi kugwa mofulumira mpaka pansi. nthawi zonse (30-35 ° C). Mu agalu aang'ono, omwe imfa imapezeka mofulumira kwambiri, sipangakhale kutentha thupi kumayambiriro kwa matendawa. Mwa agalu, pali kusowa kwa njala, kukhumudwa, kukhumudwa, kugunda kofooka, kwa ulusi (mpaka kugunda kwa 120-160 pamphindi), yomwe pambuyo pake imakhala yosasinthika. Kugunda kwa mtima kumakulitsidwa. Kupuma kumakhala kofulumira (mpaka 36-48 pamphindi) komanso kovuta, mwa agalu aang'ono nthawi zambiri amabuula. Palpation wa khoma lakumanzere pamimba (kumbuyo kwa mtengowo) kumawonetsa ndulu yokulitsa.

The mucous nembanemba m`kamwa patsekeke ndi conjunctiva ndi magazi m`thupi, icteric. Kuwonongeka kwakukulu kwa maselo ofiira amwazi kumayendera limodzi ndi nephritis. Kuyenda kumakhala kovuta, hemoglobinuria ikuwonekera. Matendawa amatha masiku 2 mpaka 5, nthawi zambiri masiku 10-11, nthawi zambiri amapha (NA Kazakov, 1982). Nthawi zambiri, hemolytic anemia imadziwika chifukwa cha kuwonongeka kwakukulu kwa maselo ofiira a m'magazi, hemoglobinuria (mkodzo umakhala wofiyira kapena wa khofi), bilirubinemia, jaundice, kuledzera, kuwonongeka kwa dongosolo lamanjenje. Nthawi zina pali chotupa pakhungu monga urticaria, hemorrhagic mawanga. Kupweteka kwa minofu ndi mafupa nthawi zambiri kumawonedwa. Hepatomegaly ndi splenomegaly nthawi zambiri amawonedwa. Agglutination wa erythrocytes mu capillaries a ubongo akhoza kuona. Popanda thandizo la panthawi yake, nyama, monga lamulo, zimafa pa tsiku la 3-5 la matendawa. Maphunziro osatha nthawi zambiri amawonedwa mwa agalu omwe kale anali ndi babesiosis, komanso nyama zomwe zimachulukitsidwa ndi thupi. Mtundu uwu wa matendawa umadziwika ndi kukula kwa magazi m'thupi, kufooka kwa minofu ndi kutopa. Mu nyama zodwala, palinso kutentha kwa 40-41 ° C m'masiku oyambirira a matendawa. Kupitilira apo, kutentha kumatsika (pafupifupi, 38-39 ° C). Zinyama zimakhala zolefuka, chilakolako chimachepa. Nthawi zambiri pamakhala kutsekula m'mimba ndi chonyezimira chachikasu cha ndowe. Kutalika kwa matendawa ndi masabata 3-8. Matendawa nthawi zambiri amatha ndi kuchira pang'onopang'ono. (PA. Kazakov, 1982 AI Yatusevich, VT Zablotsky, 1995). Nthawi zambiri m'mabuku asayansi mungapeze zambiri za tiziromboti: babesiosis, anaplasmosis, rickettsiosis, leptospirosis, etc. (AI Yatusevich et al., 2006 NV Molotova, 2007 ndi ena). Malinga ndi P. Seneviratna (1965), mwa agalu a 132 omwe anayesedwa ndi iye chifukwa cha matenda achiwiri ndi matenda, agalu a 28 anali ndi matenda a parasitic omwe amayamba chifukwa cha Ancylostoma caninum 8 - filariasis 6 - leptospirosis 15 agalu anali ndi matenda ena ndi matenda. Agalu akufawo anali atatopa. Mucous nembanemba, subcutaneous minofu ndi serous nembanemba ndi icteric. Pa matumbo mucosa, nthawi zina mfundo kapena bandege kukha magazi. Mphuno imakulitsidwa, zamkati zimafewetsedwa, kuchokera ku zofiira zowala kupita ku mtundu wakuda wa chitumbuwa, pamwamba pake ndi matope. Chiwindi chimakulitsidwa, chitumbuwa chopepuka, nthawi zambiri chimakhala chofiirira, parenchyma imapangidwa. ndulu yadzaza ndi lalanje bile. Impso zimakulitsidwa, edematous, hyperemic, capsule imachotsedwa mosavuta, cortical wosanjikiza ndi mdima wofiira, ubongo ndi wofiira. Chikhodzodzo chimadzazidwa ndi mkodzo wofiira kapena mtundu wa khofi, pa mucous nembanemba pali pinpoint kapena milozo kukha magazi. Minofu ya mtima ndi yofiyira kwambiri, ndipo kukhetsa magazi kumazungulira pansi pa epi- ndi endocardium. M'mitsempha ya mtima muli magazi "osungunuka" osatsekera. Pankhani ya hyperacute course, zosintha zotsatirazi zimapezeka mu nyama zakufa. Ma mucous nembanemba amakhala ndi chikasu pang'ono ndimu. Magazi mu ziwiya zazikulu ndi wandiweyani, mdima wofiira. M'ziwalo zambiri, pali pinpoint hemorrhages momveka bwino: mu thymus, kapamba, pansi pa epicardium, mu cortical wosanjikiza wa impso, pansi pa pleura, mu mwanabele, pamodzi nsonga za makutu a m'mimba. The kunja ndi mkati mwanabele ndi kutupa, lonyowa, imvi, ndi noticeable follicles mu cortical zone. Mphunoyo ili ndi zamkati wandiweyani, zomwe zimapereka kukanda pang'ono. Myocardium ndi yotuwa, yotuwa. Impso zimakhalanso ndi mawonekedwe osalala. Kapisozi ndi yosavuta kuchotsa. Mu chiwindi, zizindikiro za protein dystrophy zimapezeka. Mapapo ali ndi mtundu wofiira kwambiri, mawonekedwe owundana, ndipo chithovu chofiira kwambiri chimapezeka mu trachea. Mu ubongo, kusalala kwa ma convolutions kumadziwika. Mu duodenum ndi kutsogolo mbali ya Taphunzira mucous nembanemba reddened, lotayirira. M'madera ena a matumbo, pamwamba pa ntchofu amaphimbidwa ndi ntchofu wambiri wotuwa. Zipolopolo zokhala paokha ndi zigamba za Peyer ndi zazikulu, zowoneka bwino, zomwe zimakhala mu makulidwe a matumbo.

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