Eosinophilic granuloma complex mu amphaka

Kodi eosinophilic granuloma complex ndi chiyani?

Eosinophilic granuloma complex (EG) ndi mtundu wa zotupa pakhungu ndi mucous membrane, nthawi zambiri pakamwa pa amphaka. Ikhoza kufotokozedwa m'njira zitatu: chilonda cha indolent, granuloma yozungulira ndi eosinophilic plaque. Amadziwika ndi kudzikundikira m'madera ena a eosinophils - mtundu wa leukocyte umene umateteza thupi ku tizilombo toyambitsa matenda ndipo umakhudzidwa ndi chitukuko cha matupi awo sagwirizana. Mphaka aliyense akhoza kukula, mosasamala kanthu za msinkhu ndi mtundu.

Momwe mitundu yosiyanasiyana ya CEG imawonekera

• Indolent ulcer. Zimachitika pa mucous nembanemba mkamwa, kuwonetseredwa ndi kukula kwa kumtunda kapena kumunsi kwa milomo, kukokoloka kwa mucous nembanemba, kusandulika chilonda. Ndi chitukuko cha matendawa, zingakhudze mphuno ndi khungu la muzzle. Chodabwitsa ndichakuti zotupazi sizipweteka.

• Granuloma. Kuwonetseredwa m`kamwa patsekeke mu mawonekedwe a yoyera tinatake tozungulira pa lilime, mu mlengalenga, akhoza kukokoloka kapena zilonda, foci wa necrosis. Maonekedwe a mzere wa EG amawoneka ngati zingwe mkati mwa miyendo yakumbuyo, zomwe zimatuluka pamwamba pa khungu. Linear granuloma limodzi ndi kuyabwa ndi dazi. Mphaka akhoza kukhala ndi nkhawa kwambiri, kumangokhalira kunyambita.

• Plaques. Zitha kuchitika mbali iliyonse ya thupi ndi mucous nembanemba. Kutuluka pamwamba pa khungu, kungakhale ndi pinki, kulira maonekedwe. Imodzi kapena zingapo, zozungulira komanso zosakhazikika, zosalala. Pamene matenda achiwiri aphatikizidwa, pyoderma, papules, pustules, kutupa kwa purulent, komanso madera a necrosis amathanso kuchitika.

Zomwe zimayambitsa ma granulomas

Chifukwa chenicheni cha eosinophilic granuloma complex sichidziwika. Nthawi zambiri zotupa ndi idiopathic. Pali chifukwa chokhulupirira kuti zowawa, makamaka zomwe utitiri, midge, kulumidwa ndi udzudzu, zitha kuyambitsa CEG. Atopic dermatitis amathanso limodzi ndi zilonda zam'mimba, zolembera za chikhalidwe cha eosinophilic. Chakudya hypersensitivity ndi tsankho. Hypersensitivity, yomwe imadziwikanso kuti ziwengo zazakudya, ndizosowa kwambiri, zomwe zikuwonetsa kuti mphaka ndi wosagwirizana ndi mtundu wina wa mapuloteni azakudya. Mulingo wotani wa allergen umalowa m'thupi - zilibe kanthu, ngakhale ndi nyenyeswa yaying'ono, zomwe zimatha kuchitika, kuphatikiza ndi mawonekedwe amtundu umodzi kapena zingapo za eosinophilic granuloma. Ndi kusalolera, komwe kumachitika mukakumana ndi chinthu china, zizindikiro zimawonekera mwachangu ndipo zimatha msanga. Ndiko kuti, pamenepa, kupezeka kwa zolengeza, zilonda kapena zotupa liniya n`zokayikitsa.

Matenda osiyanasiyana

Kawirikawiri chithunzi cha mawonetseredwe onse a eosinophilic granuloma ndi khalidwe. Koma m'pofunikabe kutsimikizira matendawo kuti mupereke chithandizo choyenera. Ndikofunikira kusiyanitsa zovuta ndi matenda monga:

• Calicivirus, khansa ya m'magazi
• Matenda a fungal
• Squamous cell carcinoma
• Pyoderma
• Neoplasia
• Kutentha ndi kuvulala
• Matenda a chitetezo chamthupi
• Matenda a m'kamwa

Diagnostics

Matendawa amapangidwa momveka bwino pamaziko a anamnestic omwe amaperekedwa ndi mwiniwake, malinga ndi zotsatira za kafukufuku ndi njira zowunikira. Ngati mukudziwa chifukwa chake mphaka angakhale ndi vuto, onetsetsani kuti mwauza dokotala za izo. Mukachotsa izi posachedwa, mudzapulumutsa chiweto chanu ku CEG. Ngati chifukwa chake sichidziwika, kapena kuti matendawa akukayikitsa, ndiye kuti zinthuzo zimatengedwa kuti zifufuze za cytological. Mwachitsanzo, chilonda chosagwira ntchito chingasokonezedwe ndi zizindikiro za calicivirosis mu amphaka, kusiyana kokha ndiko kuti ndi kachilombo ka HIV kameneka, zilonda zimawoneka zosaopsa, koma zimakhala zowawa kwambiri. Ma smear ojambulidwa nthawi zambiri sakhala odziwitsa, amatha kuwonetsa chithunzi cha pyoderma yapamwamba, kotero kuti biopsy yabwino ya singano iyenera kutengedwa. Galasi yokhala ndi ma cell omwe apezeka imatumizidwa ku labotale kuti adziwe. Ma eosinophils ambiri amapezeka m'zinthu, zomwe zimatipatsa chifukwa cholankhulira za eosinophilic granuloma complex. Ngati, pambuyo kufufuza cytological, dokotala kapena eni ali ndi mafunso kuti akadali eosinophilic granuloma zovuta, koma matenda ena, kapena ngati mankhwala sagwira ntchito, ndiye mu nkhani iyi nkhani anatumizidwa histological kufufuza. chithandizo Chithandizo zimadalira chifukwa cha eosinophilic granuloma. Chithandizo chiyenera kutengedwa mozama. Granuloma ikhoza kubwerera ku chikhalidwe chake ngati sichichotsedwa. Inde, ngati si chikhalidwe cha idiopathic, ndiye kuti chithandizo cha zizindikiro chimagwiritsidwa ntchito. Chithandizo chimakhala ndi kutenga mahomoni kapena ma immunosuppressants kwa milungu iwiri, monga Prednisolone. Ngati eni ake sangathe kutsatira malangizo a dokotala, perekani piritsi 1 kapena 2 pa tsiku, ndiye kuti jakisoni wa mankhwalawa angagwiritsidwe ntchito, koma osavomerezeka kugwiritsa ntchito glucocorticosteroids, jekeseni imodzi yomwe imatha milungu iwiri. Izi ndichifukwa chakusadziwikiratu kwa nthawi komanso mphamvu ya mankhwalawa. Kutalika kwa mankhwala ndi pafupifupi milungu iwiri. Ngati mukuyenera kugwiritsa ntchito mankhwalawa kwa nthawi yayitali, ndiye kuti njira ya mahomoni imathetsedwa bwino komanso mosamalitsa moyang'aniridwa ndi dokotala. Koma, kachiwiri, izi kawirikawiri sizichitika ngati eni ake akutsatira ndondomeko zonse moyenera. Kuphatikiza apo, mankhwala angaphatikizepo mankhwala oletsa mabakiteriya okhala ndi mapiritsi kapena mafuta odzola. Chinthu chofunika kwambiri ndi kukhala oleza mtima ndi kutsatira malangizo a dokotala, ndiye inu ndithudi kuthandiza Pet.